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. 2020 Nov 13;3:174. doi: 10.1038/s42004-020-00411-z

Fig. 5. Activity plot for triple FXR/PPARα/δ activators.

Fig. 5

Graphical representation of pEC50 values on the targets PPARδ (abscissa), FXR (ordinate), and PPARα (bubble size). Color indicates the site of modification (orange—head group, red—anthranilamide, green—acyl substituent). The structural features of favored molecules were fused in 40 and 41 shown in blue.