Table 2.
Analysis of results.
| PDHK2d | Hsp90e | ||||
|---|---|---|---|---|---|
| koff | No PR | No SM | No PR | No SM | |
| CRM from SM1a | Fasterc | 16 | 5 | 2 | 1 |
| Slower | 19 | 3 | 26 | 22 | |
| CRM from SM2b | Fasterc | 9 | 14 | 3 | 4 |
| Slower | 2 | 2 | 7 | 14 | |
The table shows the number of PR and SM for each target for the CRMs from the two starting materials where the product gave a faster (or equal) or slower koff than the starting material.
aThere are 55 CRMs from SM1; for Hsp90, two gave native structures.
bThere are 28 CRMs from SM2.
cFaster or equal to koff for the starting material.
dkoff was not determined for 12 CRMs from SM1 and 1 CRM from SM2 for PDHK2.
ekoff was not determined for two CRMs from SM1 for Hsp90.