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. 2021 Oct 22;4:148. doi: 10.1038/s42004-021-00586-z

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© The Author(s) 2021

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Fig. 2 — Strategies, a enzymatic hydrolysis; b asymmetric hydrogenation; c chiral auxiliaries. Valuable molecules: difluoro peptides, difluoro amino alcohols, and difluoro alkaloid.