Fig. 2.
Plasma concentration of nitric oxide and its oxidation products (NOx), elevated by chronic hypoxia, is not affected by DHEA-S or simvastatin treatment. When simvastatin and DHEA-S are combined, plasma NOx no longer differs from normoxic controls. Group abbreviations as in Fig. 1; in parentheses are the ns. The columns and lines represent means and s.d., respectively. Differences among the groups not specifically marked are not statistically significant (p<0.05, 1-way ANOVA and Fischer’s least significant difference post hoc test). *p=0.0017 vs. NC, **p=0.0027 vs. NC, ***p<0.0001 vs. NC