Table 2.
Association between sleep characteristics and ePVS ratings
| Sleep characteristics | ePVS ratings | |||
|---|---|---|---|---|
| Basal ganglia | Centrum semiovale | |||
|
| ||||
| OR (95% CI) | P | OR (95% CI) | P | |
|
| ||||
| Total sleep time, min | 1.00 (0.99–1.01) | 0.663 | 1.00 (0.99–1.00) | 0.333 |
| Sleep efficiency, % | 0.99 (0.93–1.05) | 0.763 | 0.99 (0.95–1.02) | 0.433 |
| WASO, min | 1.00 (0.99–1.01) | 0.775 | 1.00 (1.00–1.01) | 0.631 |
| Apnea-Hypopnea index, events/hour | 0.87 (0.54–1.39) | 0.552 | 1.12 (0.84–1.50) | 0.434 |
| Time spent with SpO2<90%, % | 1.00 (0.96–1.05) | 0.929 | 1.02 (0.99–1.05) | 0.153 |
| N1 sleep, min | 1.01 (0.97–1.05) | 0.628 | 1.03 (1.01–1.05) | 0.008 |
| N1 sleep, % | 1.03 (0.90–1.18) | 0.710 | 1.12 (1.04–1.20) | 0.003 |
| N2 sleep, min | 1.00 (0.99–1.01) | 0.988 | 1.00 (1.00–1.01) | 0.839 |
| N2 sleep, % | 1.00 (0.96–1.05) | 0.985 | 1.01 (0.98–1.04) | 0.487 |
| N3 sleep, min | 1.00 (0.99–1.01) | 0.971 | 0.99 (0.98–1.00) | 0.028 |
| N3 sleep, % | 0.99 (0.95–1.04) | 0.734 | 0.97 (0.94–1.00) | 0.055 |
| REM sleep, min | 1.00 (0.99–1.02) | 0.724 | 1.00 (0.99–1.01) | 0.807 |
| REM sleep, % | 1.01 (0.94–1.10) | 0.746 | 1.01 (0.96–1.05) | 0.791 |
Basal ganglia and centrum semiovale ePVS rating are scored from Grade 1 to 4 (mild to severe) as a 2-level variable: grade 1 and 2 versus 3 and 4. Models were adjusted for age, sex, time interval between PSG, ApoE ε4 carrier status, hypertension, and smoking. ePVS, enlarged perivascular spaces; REM, rapid-eye movement. The apnea-hypopnea index was log-transformed.