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. 2023 Jan 5;26:100569. doi: 10.1016/j.lanepe.2022.100569

Table 2.

Maternal adverse outcomes among pregnant women tested positive for SARS-CoV-2 according to the pre-Delta, Delta, and Omicron periods.

Pre-Delta
Delta
Omicron
n = 1402
n = 262
n = 391
n % 95%CI n % 95% CI n % 95% CI
Maternal adverse outcome 47 3.4% 2.5–4.4 17 6.5% 3.8–10.2 4 1.0% 0.3–2.6
Inpatient management 176 12.6% 10.9–14.4 45 17.2% 12.8–22.3 49 12.5% 9.4–16.2
 Standard unit 131 9.3% 7.9–11.0 32 12.2% 8.5–16.8 45 11.5% 8.5–15.1
 ICU admission 45 3.2% 2.4–4.3 13 5.0% 2.7–8.3 4 1.0% 0.3–2.6
 Length ICU >7 days 12 0.9% 0.4–1.5 5 1.9% 0.6–4.4 0 0.0% 0.0–0.9
Maternal complications
 Pneumonia 33 2.4% 1.6–3.3 5 1.9% 0.6–4.4 0 0.0% 0.0–0.9
 ARDS 56 4.0% 3.0–5.2 8 3.1% 1.3–5.9 0 0.0% 0.0–0.9
Oxygen supply requirement 66 4.7% 3.7–6.0 26 9.9% 6.6–14.2 2 0.5% 0.1–1.8
 Standard oxygen 35 2.5% 1.7–3.5 13 5.0% 2.7–8.3 2 0.5% 0.1–1.8
 High Flow oxygen 12 0.9% 0.4–1.5 3 1.1% 0.2–3.3 0 0.0% 0.0–0.9
 Non-invasive ventilation 5 0.4% 0.1–0.8 3 1.1% 0.2–3.3 0 0.0% 0.0–0.9
 Mechanical ventilation 14 1.0% 0.5–1.7 7 2.7% 1.1–5.4 0 0.0% 0.0–0.9
 ECMO 7 0.5% 0.2–1.0 0 0.0% 0.0–1.4 0 0.0% 0.0–0.9
Maternal death (any reason) 3 0.2% 0.0–0.6 0 0.0% 0.0–1.4 0 0.0% 0.0–0.9

ICU: intensive care unit, ARDS: acute respiratory distress syndrome, ECMO: extracorporeal membrane oxygenation.