Table 2.
Maternal adverse outcomes among pregnant women tested positive for SARS-CoV-2 according to the pre-Delta, Delta, and Omicron periods.
|
Pre-Delta |
Delta |
Omicron |
|||||||
|---|---|---|---|---|---|---|---|---|---|
|
n = 1402 |
n = 262 |
n = 391 |
|||||||
| n | % | 95%CI | n | % | 95% CI | n | % | 95% CI | |
| Maternal adverse outcome | 47 | 3.4% | 2.5–4.4 | 17 | 6.5% | 3.8–10.2 | 4 | 1.0% | 0.3–2.6 |
| Inpatient management | 176 | 12.6% | 10.9–14.4 | 45 | 17.2% | 12.8–22.3 | 49 | 12.5% | 9.4–16.2 |
| Standard unit | 131 | 9.3% | 7.9–11.0 | 32 | 12.2% | 8.5–16.8 | 45 | 11.5% | 8.5–15.1 |
| ICU admission | 45 | 3.2% | 2.4–4.3 | 13 | 5.0% | 2.7–8.3 | 4 | 1.0% | 0.3–2.6 |
| Length ICU >7 days | 12 | 0.9% | 0.4–1.5 | 5 | 1.9% | 0.6–4.4 | 0 | 0.0% | 0.0–0.9 |
| Maternal complications | |||||||||
| Pneumonia | 33 | 2.4% | 1.6–3.3 | 5 | 1.9% | 0.6–4.4 | 0 | 0.0% | 0.0–0.9 |
| ARDS | 56 | 4.0% | 3.0–5.2 | 8 | 3.1% | 1.3–5.9 | 0 | 0.0% | 0.0–0.9 |
| Oxygen supply requirement | 66 | 4.7% | 3.7–6.0 | 26 | 9.9% | 6.6–14.2 | 2 | 0.5% | 0.1–1.8 |
| Standard oxygen | 35 | 2.5% | 1.7–3.5 | 13 | 5.0% | 2.7–8.3 | 2 | 0.5% | 0.1–1.8 |
| High Flow oxygen | 12 | 0.9% | 0.4–1.5 | 3 | 1.1% | 0.2–3.3 | 0 | 0.0% | 0.0–0.9 |
| Non-invasive ventilation | 5 | 0.4% | 0.1–0.8 | 3 | 1.1% | 0.2–3.3 | 0 | 0.0% | 0.0–0.9 |
| Mechanical ventilation | 14 | 1.0% | 0.5–1.7 | 7 | 2.7% | 1.1–5.4 | 0 | 0.0% | 0.0–0.9 |
| ECMO | 7 | 0.5% | 0.2–1.0 | 0 | 0.0% | 0.0–1.4 | 0 | 0.0% | 0.0–0.9 |
| Maternal death (any reason) | 3 | 0.2% | 0.0–0.6 | 0 | 0.0% | 0.0–1.4 | 0 | 0.0% | 0.0–0.9 |
ICU: intensive care unit, ARDS: acute respiratory distress syndrome, ECMO: extracorporeal membrane oxygenation.