Table 3.
Clinicopathological and prognostic values of LINC00324 in cancer.
Cancers | LINC00324 expression | Clinical samples | Clinicopathological characteristics | Prognosis | Reference |
---|---|---|---|---|---|
BC | deregulated | 960 patients via TCGA and GEO database; 39 BC patients | Larger tumor size and volume | worse OS | (22) |
GC | upregulated | 66 paired GC tissues and adjacent normal tissues | more advanced TNM stage;larger tumor size; higher lymph node metastasis | worse OS and DFS | (15) |
upregulated | 60 GC patients | larger tumor size; higher lymphoma metastasis;more advanced TNM stage | — | (14) | |
HCC | upregulated | 125 patients via GEO database | larger tumor size; more advanced clinical stage;higher tumor differentiation degree; higher lymph node metastasis | worse OS | (17) |
IOT | upregulated | 45 paired IOT tissues and MOT tissues | — | worse OS | (9) |
NSCLC | upregulated | 48 NSCLC tissues and 18 adjacent normal tissues | higher rate of lymph node metastasis | worse OS | (11) |
RB | upregulated | 47 RB tissues and 13 normal retinal tissues | more advanced TNM stage;higher optic nerve invasion degree | worse OS | (19) |
SaOS | upregulated | 86 osteosarcoma tissues and 86 noncancerous tissues | larger tumor size; further distant metastasis; more advanced TNM stage; more malignant differentiated degree | worse OS | (16) |