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. 2023 Jan 5;18(1):e0280109. doi: 10.1371/journal.pone.0280109

Table 2. Factors associated with SARS-CoV-2 seropositivity by Roche.

Total N = 763 SARS-CoV-2 seropositive N = 221 (29%) SARS-CoV-2 seronegative N = 542 OR (95%CI) p-value
Age
    <30 years 409 (53.6) 129 (58.4) 280 (51.7) 1
    ≥30 years 354 (46.4) 92 (41.6) 262 (48.3) 0.8 (0.6–1.0) 0.092
Ethnicity
    White 283 (37.2) 80 (36.4) 203 (37.6) 1
    Non-white 477 (62.8) 140 (63.6) 337 (62.4) 1.1 (0.8–1.5) 0.751
Occupation
Healthcare 52 (6.9) 17 (8.0) 35 (6.5) 1
Essential non-healthcarea 90 (12.0) 30 (14.1) 60 (11.2) 1.0 (0.5–2.2) 0.938
Non-essential 607 (81.0) 166 (77.9) 441 (82.3) 0.8 (0.4–1.5) 0.410
Any comorbidity b
    No 613 (80.3) 179 (81.0) 434 (80.1) 1
    Yes 150 (19.7) 42 (19.0) 108 (19.9) 0.9 (0.6–1.4) 0.771
BMI (kg/m2) 31.3 (5.9) 32.1 (6.2) 31 (5.8) 1.03 (1.00–1.06) 0.024
Height (cm) 160.8 (6.5) 159.5 (6.1) 161.3 (6.6) 0.96 (0.93–0.98) 0.001
Potential COVID-19 symptoms during pregnancy
Fever 78 (10.2) 45 (20.4) 33 (6.1) 3.9 (2.4–6.4) <0.001
Cough 134 (17.6) 68 (30.8) 66 (12.2) 3.2 (2.2–4.7) <0.001
Sore throat 80 (10.5) 42 (19.0) 38 (7.0) 3.1 (1.9–5.0) <0.001
Myalgia 98 (12.8) 64 (29.0) 34 (6.3) 6.1 (3.9–9.7) <0.001
Asthenia 89 (11.7) 58 (26.2) 31 (5.7) 5.9 (3.7–9.5) <0.001
Coryza 164 (21.5) 79 (35.7) 85 (15.7) 3.0 (2.1–4.3) <0.001
Anosmia 86 (11.3) 74 (33.5) 12 (2.2) 22.2 (12.2–44.1) <0.001
Ageusia 82 (10.7) 71 (32.1) 11 (2.0) 22.8 (12.3–46.6) <0.001
Dyspnea 72 (9.4) 51 (23.1) 21 (3.9) 7.4 (4.4–13.0) <0.001
Headache 137 (18.0) 75 (33.9) 62 (11.4) 4.0 (2.7–5.9) <0.001
Fatigue 82 (10.7) 55 (24.9) 27 (5.0) 6.3 (3.9–10.5) <0.001
No symptoms 490 (64.2) 93 (42.1) 397 (73.2) 0.3 (0.2–0.4) <0.001

Data shown as frequency, n/N (%) or mean (±SD)

BMI = body mass index; CI = confidence interval; OR = odds ratio

a Essential workers defined as those working with food supply or hospital services such as cleaning and hospitality

b Any comorbidity includes diabetes, hypertension, cardiac, lung, rheumatic diseases, cancer and thromboembolic events