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. 2022 Dec 16;13:1057376. doi: 10.3389/fendo.2022.1057376

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Copyright © 2022 Han, Lin, Lu, Wang, Tang, Tao, Cai, He and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Time-restricted feeding (TRF) prevents weight gain and reduces body fat mass in mice. Growth curves and body fat composition for four groups. HA group: high-fat diet (HFD) feeding mice with ad libitum; dihydrotestosterone (DHEA) and ad libitum feeding (DA) group: mice were given an HFD and water ad libitum; HFD and TRF intervention (HT) group: mice were given an HFD as well as a TRF dietary pattern; DHEA and TRF intervention (DT) group: mice were given an HFD as well as a TRF dietary pattern. (A) Growth curves for four groups. (B, C) Body fat test. Values are mean ± SEM. *P<0.05, **P < 0.01, ***P< 0.001, ****P<0.0001, DA group vs. DT group; ^###P<0.001, ^####P<0.0001, HA group vs. HT group.