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. 2022 Dec 16;13:1057376. doi: 10.3389/fendo.2022.1057376

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Copyright © 2022 Han, Lin, Lu, Wang, Tang, Tao, Cai, He and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TRF ameliorates hyperandrogenemia in PCOS mice. (A) Plasma testosterone levels. (B) Plasma luteinizing hormone (LH) levels. (C) Plasma follicle-stimulating hormone (FSH) levels. (D)The ratio of LH to FSH. (E) Plasma estradiol (E2) levels. All data were presented as mean ± SEM. *P < 0.05, **P < 0.01, ****P < 0.0001, DA group vs. DT group; *P < 0.05, **P < 0.01, ****P < 0.0001, DA group vs. DT group; ^#### P < 0.0001, HA group vs. HT group. ^P < 0.05, ^^P < 0.01, ^^^^P < 0.0001, DA group vs. HA group.