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. 2022 Dec 21;10:1025633. doi: 10.3389/fpubh.2022.1025633

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Copyright © 2022 Shariati, Arshadi, Khosrojerdi, Abedinzadeh, Ganjalishahi, Maleki, Heidary and Khoshnood.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ciprofloxacin's mechanisms of action (13). Because ciprofloxacin blocks DNA gyrase and topoisomerase IV, DNA replication is slowed and double-stranded DNA breaks are created.