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. 2022 Dec 22;12:1025594. doi: 10.3389/fonc.2022.1025594

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Copyright © 2022 Huang, Xia, Guo, Huang, Wang, Huang, Qin, Leng and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of potential target genes of miR-194 by RNA sequencing. (A) A total of 96 genes greatly downregulated by miR-194 in GSE137070 dataset were screened (log2FC<-1). (B) After transfection with miR-194 mimics in GC cell lines SGC7901 and AGS, RNA-seq studies were conducted to explore target genes of miR-194 (GSE134308). A total of 34 genes greatly downregulated by miR-194 (log2FC<-0.8) were screened according to RNA-seq analysis. (C) A total of 18 genes greatly downregulated by miR-194 in both GSE137070 and GSE134308 datasets were screened. **P < 0.01.