DI |
dimethyl itaconate |
Acod1 |
aconitate decarboxylase 1 |
AD |
Alzheimer’s disease |
Tg |
Toxoplasma gondii
|
Con |
control |
Veh |
vehicle |
TEM |
transmission electron microscope |
IF |
immunofluorescence |
SYN |
synaptophysin |
PSD95 |
postsynaptic density 95 |
SC |
synaptic cleft |
SV |
synaptic vesicle |
Iba1 |
ionized calcium-binding adaptor molecule1 |
IL-1β |
interleukin-1 beta |
IL-6 |
interleukin-6 |
TNF-α |
tumor necrosis factor-α |
IRG1 |
immune responsive gene 1 |
TCA |
tricarboxylic acid |
RNA-seq |
genome-wide RNA-sequencing |
GSEA |
gene set enrichment analysis |
NES |
normalized enrichment score |
SEM |
standard error of the mean |
ANOVA |
analysis of variance |
FDR |
false discovery rate |
NL |
novel location |
NOR |
novel object recognition |
ddH2O |
double-distilled water |
CA1 |
cornu ammonis 1 |
CA3 |
cornu ammonis 3 |
DG |
dentate gyrus |
PBS |
phosphate buffered solution |
qPCR |
quantitative real-time PCR |
DEGs |
differential expression genes |
GO |
Gene Ontology |
KEGG |
Kyoto Encyclopedia of Genes and Genomes |
P value |
probability |
CC |
cellular component |
MF |
molecular function |
BP |
biological process |
GABA |
γ-aminobutyric acid |
NF-κB |
nuclear factor kappa-B |
JAK-STAT |
Janus kinase-signal transducer and activator of transcription |
Aif1 |
allograft inflammatory factor 1 |
Cd86 |
cluster of differentiation 86 |
Cd40 |
cluster of differentiation 40 |
Ccl2 |
C-C motif ligand 2 |
Ccr2 |
C-C motif chemokine receptor 2 |
Cx3cr1 |
C-X3-C motif chemokine receptor 1 |
Nos2 |
nitric oxide synthase 2 |
Sdhaf3 |
succinate dehydrogenase assembly factor 3 |
Sucla2 |
succinate-CoA ligase [ADP-forming] subunit beta |
Suclg2 |
succinate–CoA ligase [GDP-forming] subunit beta |
Idh3a |
isocitrate dehydrogenase 3 catalytic subunit alpha |
Mdh2 |
malate dehydrogenase 2, mitochondrial |
Atf3 |
activating transcription factor 3 |
Nqo2 |
N-ribosyldihydronicotinamide: quinone reductase 2 |
Stat3 |
signal transducer and activator of transcription 3 |
Psmb9 |
proteasome 20S subunit beta 9 |
Nfe2l2 |
nuclear factor erythroid-derived 2 like 2 |
Nrf2 |
nuclear factor erythroid2-related factor 2 |
Hk |
hexokinase |
Phi |
phosphate isomerase |
Pfkfb |
fructose-2,6-biphosphatase |
Pfk |
phosphofructokinase |
Aldo |
aldolase |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
Pgk1 |
phosphoglycerate kinase 1 |
Pk |
pyruvate kinase |
Pdh |
pyruvate dehydrogenase complex |
Cs |
citrate synthase |
Aco |
aconitase |
Idh |
isocitrate dehydrogenase |
αKGDH |
α-ketoglutarate dehydrogenase |
Sdh |
succinate dehydrogenase |
Fh |
fumarate hydratase |
Mdh |
malate dehydrogenase |
CNS |
central nervous system |
Tnfaip3 (A20) |
tumor necrosis factor alpha-induced protein 3 |
Hmox1 |
heme oxygenase 1 |
Tap1 |
transporter 1 |
LPS |
lipopolysaccharide |