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Effects of arctigenin (AG), burdock sprout extract (GSE), and metformin (MF) on the body composition of mice fed a high-fat, high-sucrose (HFHS) diet. Mice were fed a normal diet (ND), HFHS, HFHS + AG (0.5%), HFHS + GSE (5%), or HFHS + MF (0.5%) for 8 weeks. (A) Weight gain curves; (B) average energy intake; and (C) liver, (D) epididymal fat, and (E) mesenteric fat weights. Data are expressed as the mean ± SEM. *p<0.05 versus the HFHS group (n=6). **p<0.01 versus the HFHS group (n=6).
