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. 2023 Jan 5;14:77. doi: 10.1038/s41467-022-35727-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Top: Clinical and genomic features of the tumors (number of structural variants (SVs), presence of chromothripsis, prior platinum treatment, HRD pathway mutation). Bottom: SBS mutational signatures corresponding to COSMIC mutational signatures V3.2, scaled by mutation burden in tumor (above) and scaled to proportions of 1 for each tumor (below). X-axis depicts individual tumors. Source data are provided as a Source Data file.