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. 2022 Sep 22;50(2):602–612. doi: 10.1007/s00259-022-05974-8

Table 1.

Patient characteristics (n = 20)

Variable
Age (years, mean ± SD) 72.1 ± 8.6
Gleason score (mean ± SD) 9 ± 1
Previous treatments (%)
Radical prostatectomy 45
Primary radiation therapy 15
Salvage radiation therapy 65
Androgen deprivation therapy 100
Enzalutamide 75
Abiraterone acetate 90
Previous chemotherapy 95
Docetaxel 95
Cabazitaxel 50
Laboratory values at baseline (mean ± SD)
AST (U/I) 59 ± 84
ALT (U/I) 21 ± 12
AP (U/I) 241 ± 194
LDH (U/I) 515 ± 420
PSA (μg/L) 309.8 ± 418.3
Site of tumor lesions (%)
Skeleton 100
Lymph nodes 90
Liver 10
Prostate/Prostate bed 55
PET-based parameters at baseline (mean ± SD)
SUVmax 19.4 ± 11.4
SUVmean 12.6 ± 8.2
PSMA-TV (cm3) 226.5 ± 195.8

ALT, alanine transaminase; AP, alkaline phosphatase; AST, aspartate transaminase; LDH, lactate dehydrogenase; PET, positron emission tomography; PSA, prostate-specific antigen; PSMA, prostate-specific membrane antigen; RLT, Radioligand therapy; SUV, standardized uptake value; TV, tumor volume