Table 1.
Patient characteristics (n = 20)
Variable | |
---|---|
Age (years, mean ± SD) | 72.1 ± 8.6 |
Gleason score (mean ± SD) | 9 ± 1 |
Previous treatments (%) | |
Radical prostatectomy | 45 |
Primary radiation therapy | 15 |
Salvage radiation therapy | 65 |
Androgen deprivation therapy | 100 |
Enzalutamide | 75 |
Abiraterone acetate | 90 |
Previous chemotherapy | 95 |
Docetaxel | 95 |
Cabazitaxel | 50 |
Laboratory values at baseline (mean ± SD) | |
AST (U/I) | 59 ± 84 |
ALT (U/I) | 21 ± 12 |
AP (U/I) | 241 ± 194 |
LDH (U/I) | 515 ± 420 |
PSA (μg/L) | 309.8 ± 418.3 |
Site of tumor lesions (%) | |
Skeleton | 100 |
Lymph nodes | 90 |
Liver | 10 |
Prostate/Prostate bed | 55 |
PET-based parameters at baseline (mean ± SD) | |
SUVmax | 19.4 ± 11.4 |
SUVmean | 12.6 ± 8.2 |
PSMA-TV (cm3) | 226.5 ± 195.8 |
ALT, alanine transaminase; AP, alkaline phosphatase; AST, aspartate transaminase; LDH, lactate dehydrogenase; PET, positron emission tomography; PSA, prostate-specific antigen; PSMA, prostate-specific membrane antigen; RLT, Radioligand therapy; SUV, standardized uptake value; TV, tumor volume