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Performance of combined models for the testing cohort
| Model | AUC | 95% CI | Accuracy (%) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|---|---|
| TBR-TTP | 0.74 | (0.61–0.86) | 64.3 | 50.0 | 70.0 | 40.0 | 77.8 |
| Clinical-TBR | 0.64 | (0.47–0.81) | 59.5 | 58.3 | 60.0 | 36.8 | 78.3 |
| Clinical-TTP | 0.74 | (0.60–0.88) | 69.0 | 66.7 | 70.0 | 47.1 | 84.0 |
| Clinical-TBR-TTP | 0.72 | (0.59–0.86) | 69.0 | 58.3 | 73.3 | 46.7 | 81.5 |
CI confidence interval, TBR tumor-to-background ratio, TTP time-to-peak
