Table 3.

Phenotypes of supernumerary teeth-related syndromes

Syndrome	Oral symptoms	Other symptoms	Reference
Cleidocranial dysplasia	Delayed eruption of permanent teeth Hypoplastic maxilla Characteristic shapes of the ramus, condyle, and coronoid	Abnormal clavicles Patent sutures and fontanelles Short stature Pectus excavatum Sinus and middle ear infections	206–209
Familial adenomatous polyposis	Unerupted teeth Congenital teeth missing Dentigerous cysts Odontomas	Adenomas in the rectum and colon Osteomas Congenital hypertrophy of the retinal Pigment epithelium (CHRPE) Desmoid tumours	84,210
Nance-Horan syndrome	Notched incised edges (Hutchinson’s incisors) Mulberry molars Talon’s cusp Taurodontism	Congenital cataract Strabismus	211–213
Oculofaciocardiodental syndrome	Radiculomegaly facial anomalies cleft palate	Microphthalmia Congenital cataracts Cardiac and digital abnormalities neuropathy Muscle hypotonia Pituitary underdevelopment Brain atrophy Lipoma Childhood lymphoma	214–216
Opitz BBB/G syndrome	Cleft lip and palate Micrognathia Ankyloglossia High-arched palate	Hypertelorism Hypospadias Laryngo–tracheo–oesophageal abnormalities Neurological, anal, and cardiac defects Dysphagia Developmental delay	217–219
Robinow syndrome	Midline clefting of the lower lip Gum hypertrophy Dental crowding Ankyloglossia or “tongue tie” (bifid tongue)	Hypertelorism Nasal features (large nasal bridge, short upturned Nose, and anteverted nares) Midface hypoplasia Mesomelic limb shortening Brachydactyly Clinodactyly Micropenis Short stature Umbilical hernia	220,221
Rubinstein–Taybi syndrome 1 Rubinstein–Taybi syndrome 2	High palate	Moderate-to-severe intellectual disability Downslanted palpebral fissures Low-hanging columella Grimacing smile Talon cusps Short stature Obesity Eye anomalies	222,223
Trichorhinophalangeal syndrome type I	Thin upper lip Small jaw	Relative macrocephaly Sparse hair Bulbous nasal tip Protruding ears Prominent forehead Short hands and feet Bulbous pear-shaped nose Tented alae Long-extended philtrum Horizontal groove on the chin.	224,225