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Potential mechanism of wogonin sensitization (A) “wogonin-target-gemcitabine resistance” network map. Wogonin can enhance gemcitabine sensitivity by downregulating AKT2. (B) Go enrichment analysis of 15 DEGs, which were enriched in protein kinase B (Akt) signaling. (C) Hypothesis on the sensitization mechanism of wogonin to gemcitabine in pancreatic cancer.
