TABLE 2.
IL-10 secretion by monocytes from Q fever patientsa
| Subjects | IL-10 secretion (pg/ml) with:
|
|
|---|---|---|
| Unstimulated cells | C. burnetii- stimulated cells | |
| Healthy individuals | 47 ± 32 | 699 ± 194 |
| Patients with acute Q fever | 250 ± 164 | 574 ± 362 |
| Patients with Q fever endocarditis | 1,054 ± 219b | 1,552 ± 222b |
a
Monocytes from 12 controls, 8 patients with acute Q fever, and 10 patients with ongoing Q fever endocarditis were incubated with C. burnetii at a bacterium-to-cell ratio of 200:1 for 24 h. Supernatants were assayed by ELISA for the presence of IL-10.
b
P of <0.03 represents the comparison between patients with acute Q fever and patients with Q fever endocarditis.