Table 4.
Comparison of treatment response by MTHFR C677T genotype.
| MTHFR C677T genotype | NRS | Folic acid treatment group | Conventional treatment group | t | P 1 |
|---|---|---|---|---|---|
| NRS pre-treatment | 4.29 ± 1.33 | 3.64 ± 1.91 | 1.036 | 0.309 | |
| TT | NRS post-treatment | 0.64 ± 0.63 | 1.07 ± 1.21 | 1.177 | 0.25 |
| Variation of NRS pre-and post-treatment | 3.64 ± 1.39 | 2.57 ± 1.09 | 2.267 | 0.0319 | |
| n | 14 | 14 | |||
| NRS pre-treatment | 3.83 ± 2.12 | 3.33 ± 2.19 | 0.932 | 0.354 | |
| CT | NRS post-treatment | 0.96 ± 1.04 | 0.65 ± 0.80 | 1.428 | 0.156 |
| Variation of NRS pre-and post-treatment | 2.88 ± 1.40 | 2.69 ± 0.22 | 0.623 | 0.6225 | |
| n | 24 | 48 | |||
| NRS pre-treatment | 4.429 ± 2.37 | 3.75 ± 1.58 | 0.918 | 0.365 | |
| CC | NRS post-treatment | 1.00 ± 0.57 | 0.64 ± 0.62 | 1.377 | 0.177 |
| Variation of NRS pre-and post-treatment | 3.43 ± 1.99 | 3.14 ± 1.18 | 0.497 | 0.623 | |
| n | 7 | 28 |
1
Comparisons were performed between folic acid treatment group and conventional treatment group among different MTHFR C677T genotypes at different time point.