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. 2022 Dec 23;10:1110513. doi: 10.3389/fbioe.2022.1110513

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Copyright © 2022 Geng, Liu, Chen, Wu, Wang, Zhou, Li, Li and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The ROS accumulation of ZM4 and ZMNP responding to different inhibitors. (A) ROS accumulation detection under RM with or without inhibitors. (B) ROS accumulation detection under MM with or without inhibitors. Data presented in the graphs are the mean ± SD of three replications. T-test analysis was conducted for ROS detection with RM/MM-ZM4 (black asterisk), RMF/MMF-ZM4 (green asterisk) or RME/MME (blue asterisk) condition as the control. ns represents no significant difference (p-value > 0.05), * represents a significant difference (0.01< p-value < 0.05), ** represents a significant difference (0.001 < p-value < 0.01), *** represents a significant difference (p-value < 0.001).