Table 2.
Risk of Developing Cervical Cancer according to Metformin Use
| Cancer cases (%) |
Incidence of cancer, /100,000 person-years |
Hazard ratio (95% CI) |
|||
|---|---|---|---|---|---|
| Metformin non-user | Metformin user | Metformin non-user | Metformin user | Univariate | Multivariatea |
| 274 (0.42) | 219 (0.33) | 30.5 | 24.2 | 0.805 (0.674–0.961)b | 0.783 (0.655–0.936)b |
CI, confidence interval.
a
The comparisons were made using metformin non-users as the reference group. The hazard ratio was adjusted for age, economic status, region of residence, and anti-diabetic medications (sulfonylureas, thiazolidinediones, dipeptidyl peptidase 4 inhibitors, alpha-glucosidase inhibitors, and meglitinide);
b
P<0.05.