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. 2022 Dec 23;13:989286. doi: 10.3389/fimmu.2022.989286

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Copyright © 2022 Wang, Wang, Yang, Zeng, Zhang, Liu and Pan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cuproptosis related genes for stratification in tumor cell-enriched region and immune cell-enriched regions. (A) Principal Component Analysis in tumor cell-enriched region. (B) Differential analysis in Tumor cell-enriched region, green for downregulation, red for upregulation, log|FC|>1 and P<0.05. (C) Univariate Cox analysis in tumor cell-enriched region. (D) Differential expression of cuproptosis related genes and Jab1 between high and low score groups. (E) Typing in Tumor cell-enriched region: four clusters. Typing in immune cell-enriched region: two clusters (F) GSVA for high and low score groups in tumor cell-enriched regions and immune cell-enriched regions. *p<0.05, **p<0.01, ***p<0.001, ns, not significant.