. 2022 Dec 23;13:1064328. doi: 10.3389/fmicb.2022.1064328

Table 3.

Relative abundance (%) of Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria and their top families in intestinal digesta of enterotoxigenic E. coli challenged pigs fed diets supplemented with antibiotics (AGP) or B. subtilis (DFM).

	Jejunal digesta				Ileal digesta				Colon digesta
	Negative control	Positive control	AGP	DFM	Negative control	Positive control	AGP	DFM	Negative control	Positive control	AGP	DFM
Firmicutes	93.20^ab	84.11^bcde	89.51^abc	91.85^abc	93.28^a	92.77^abc	86.08^abcd	95.67^a	85.64^cde	80.75^de	74.89^e	81.23^de
Bacillaceae	0.03^cde	0.07^cd	0.27^b	0.64^a	0.00^e	0.06^cde	0.02^cde	0.18^ab	0.00^e	0.00^e	0.00^de	0.02^c
Clostridiaceae1	2.89^bc	1.78^c	4.91^bc	3.59^bc	11.89^a	11.96^ab	22.22^a	2.88^abc	7.22^ab	1.46^bc	13.56^ab	2.35^bc
Lachnospiraceae	0.46^bc	1.52^b	0.43^bc	2.55^bc	0.13^d	0.42^bc	2.04^cd	0.09^d	23.19^a	23.15^a	21.93^a	24.36^a
Lactobacillaceae	76.09^a	60.26^ab	59.44^ab	70.54^a	47.48^b	56.22^ab	22.98^c	77.12^a	15.09^cd	14.42^cd	4.11^d	21.20^c
Peptostreptococcaceae	3.82^bc	0.06^c	3.50^ab	2.14^bc	9.59^a	5.24^ab	15.18^a	3.82^ab	3.96^a	0.86^ab	7.48^a	1.42^ab
Ruminococcaceae	0.06^cde	0.44^bc	0.13^b	1.55^cde	0.01^de	0.04^cde	2.59^bcd	0.01^e	15.52^a	18.15^a	15.24^a	15.75^a
Streptococcaceae	4.93^abc	9.61^ab	18.40^a	5.69^abc	19.42^a	12.98^abc	11.01^abc	8.94^abc	10.78^a	6.60^bcd	0.09^d	3.21^cd
Veillonellaceae	4.40^cd	6.30^abcd	0.09^g	3.85^cde	1.38^efg	1.98^def	1.21^fg	0.93^fg	6.63^abc	12.32^a	8.09^bcd	9.81^ab

Bacteroidetes	0.03^bc	0.02^bc	0.01^bc	1.08^bc	0^bc	0.03^bc	4.16^b	0^c	7.25^a	7.35^a	12.41^a	9.96^a
Bacteroidaceae	0^b	0^b	0^b	0^b	0^b	0^b	0.06^b	0^b	0.01^b	0.11^b	0.16^a	0.01^b
Muribaculaceae	0^c	0.01^c	0.01^c	0.11^bc	0^c	0^c	0.49^b	0^c	2.22^a	1.74^a	1.94^a	2.09^a
Prevotellaceae	0.03^bc	0.01^b	0^c	0.94^bc	0^c	0.03^bc	2.98^b	0^bc	4.64^a	5.09^a	8.93^a	7.23^a
Rikenellaceae	0^d	0^cd	0^d	0.03^cd	0^d	0.01^cd	0.54^c	0^d	0.28^ab	0.35^b	1.17^a	0.57^ab

Actinobacteria	4.76^a	9.43^a	1.79^abc	4.37^a	2.93^abc	4.38^ab	0.36^c	3.35^abc	2.26^abc	2.99^abc	0.5^bc	2.48^ab
Actinomycetaceae	0.01^bc	0.14^a	0.07^b	0.05^b	0^c	0.06^b	0^c	0.01^bc	0^c	0^c	0^c	0^c
Atopobiaceae	0.43^ab	0.54^a	0^b	0.32^ab	0.13^ab	0.17^ab	0.07^ab	0.09^ab	0.36^ab	1.45^ab	0.28^ab	1.01^ab
Bifidobacteriaceae	4.22^a	8.21^a	0.04^b	3.81^a	2.76^a	3.94^a	0.11^b	3.20^a	1.67^a	1.10^ab	0.01^b	1.22^a
Coriobacteriaceae	0^c	0^c	0^c	0.02^c	0^c	0^c	0.05^c	0^c	0.21^ab	0.38^a	0.20^b	0.22^ab
Eggerthellaceae	0.06^ab	0.21^a	0^b	0.05^ab	0.03^ab	0.05^ab	0^b	0.02^ab	0.02^ab	0.05^ab	0.01^ab	0.03^ab
Micrococcaceae	0.04^c	0.32^ab	1.51^a	0.11^bc	0.01^d	0.15^bc	0.12^bc	0.03^c	0^d	0^d	0^d	0^d

Proteobacteria	1.89^b	0.4^b	4.12^a	0.22^b	3.77^ab	2.21^ab	7.61^a	0.92^b	1.69^ab	4.84^a	4.6^a	2.08^a
Burkholderiaceae	0^a	0^a	0.04^a	0^a	0^a	0^a	0.41^a	0^a	0^a	0.01^a	0^a	0^a
Desulfovibrionaceae	0^b	0^b	0^b	0.01^b	0^b	0^b	0.04^b	0^b	0.07^a	0.1^a	0.14^a	0.11^a
Enterobacteriaceae	0.17^c	0.02^abc	0.04^abc	0.01^c	3.56^a	0.64^ab	0.71^bc	0.04^bc	0.07^abc	0.01^c	0.01^c	0.01^c
Pasteurellaceae	1.7^bc	0.29^bcd	3.75^a	0.02^bcd	0.21^bcd	1.54^ab	4.85^a	0.87^bc	0^cd	0.01^bcd	0^cd	0^d
Succinivibrionaceae	0^d	0.01^cd	0.09^bc	0.15^cd	0^d	0^cd	1.5^bc	0^d	1.41^b	4.71^a	4.45^a	1.94^a

^a–gMeans without a common superscript are different (p < 0.05). Each mean represents 7 observations on day −7 and each mean represents 9–12 observations on day 0 and day 7 and 21 post-inoculation.