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Taxonomic composition (A–D) and principal coordinate analysis (E–H) of the gut microbiome derived from the urine extracellular vesicles of patients with colorectal cancer and healthy controls. (A) Phylum level, (B) family level, (C) genus level, (D) alpha-diversity, (E) UniFrac distance, (F) weighted-UniFrac distance, (G) Bray-Curtis dissimilarity, and (H) Jacaard distance. CRC, colorectal cancer; OTU, operational taxonomic unit. a p ≤ 0.0001.
