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. 2022 Dec;10(23):1280. doi: 10.21037/atm-22-5444

Figure 5.

Figure 5

High expression of TMED2/3/4/9 indicated the immune-suppressive status in breast cancer. (A) Analysis of the relationship between the expressions of immune checkpoint genes and TMED2/3/4/9 mRNA levels was performed by the Sangerbox webtool. (B) GO enrichment analysis of the top 200 co-expressed genes of TMED2/3/4/9 generated by Metascape. (C) The interactome network of TMED2/3/4/9 and their common immune-related genes predicted by GeneMANIA database. *, P<0.05; **, P<0.01; ***, P<0.001. TMED, transmembrane p24 trafficking protein; BRCA, breast carcinoma; mRNA, messenger RNA; GO, Gene Ontology.