Table 3.
Changes in PFT metrics following radiotherapy for the study cohort
| PFT metric | Mean ± SD | Range |
|---|---|---|
| DLCO change* | ||
| Raw | –1.4 ± 5.1 | –14.6 to 14.5 |
| Predicted, %† | –11.6 ± 14.2 | –50.0 to 27.0 |
| FEV1 change‡ | ||
| Raw | –0.2 ± 0.5 | –2.1 to 1.3 |
| Predicted, %† | –5.6 ± 16.9 | –59.0 to 24.0 |
| FVC change‡ | ||
| Raw | –0.3 ± 0.6 | –2.5 to 0.7 |
| Predicted, %† | –9.0 ± 20.1 | –61.0 to 27.0 |
| FEV1/FVC ratio change‡ | 1.7 ± 8.0 | –32.0 to 19.0 |
Abbreviations: DLCO = diffusing capacity for carbon monoxide; FEV1 = forced expiratory volume in 1 second; FVC = forced vital capacity; PFT = pulmonary function test; SD = standard deviation.
⁎
DLCO raw values are recorded in milliliters per millimeter mercury per minute.
†
Predicted percentage takes into account patient height, sex, and age; change metrics were calculated by subtracting the posttreatment raw and predicted percentage values from the pretreatment raw and predicted percentage values.
‡
FEV1 and FVC raw values are recorded in liters.