Table 4.
Pretreatment to posttreatment PFT change for patients with and without grade 2 or higher RP
PFT metric | Mean ± SD | Range | P value |
---|---|---|---|
DLCO | |||
Grade 2 or higher RP | –15.4 ± 14.0 | –45.0 to 4.0 | .37 |
Less than grade 2 RP | –10.8 ± 14.1 | –50.0 to 27.0 | |
FEV1 | |||
Grade 2 or higher RP | –14.3 ± 22.1 | –59.0 to 13.0 | .09 |
Less than grade 2 RP | –3.9 ± 15.4 | –47.0 to 24.0 |
Abbreviations: DLCO = diffusing capacity for carbon monoxide; FEV1 = forced expiratory volume in 1 second; PFT = pulmonary function test; SD = standard deviation; RP = radiation pneumonitis.
Numbers reported represent change metrics, which were calculated by subtracting the posttreatment predicted percentage values from the pretreatment predicted percentage values. P values were obtained using unpaired t test analysis with a significance level of .05.