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. 2022 Nov 29;13(12):2244. doi: 10.3390/genes13122244

Figure 6.

Figure 6

Diabetic mice show renal injury and upregulated ASH2L and HIPK2 allied with fibrosis and inflammation. (A) Western blot analysis of ASH2L, HIPK2, and H3K4me3 in STZ-induced mice (n = 5) and db/db mice (n = 3). (B) Western blot analysis of fibrosis markers and inflammatory markers in STZ-induced mice (n = 5) and db/db mice (n = 3). (C) Blood glucose of STZ-induced mice (n = 10) and db/db mice (n = 6). Data are shown as mean ± S.D and *** p < 0.001. (D) Representative images of H&E staining, PAS staining, and Masson’s staining of mice kidneys.