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. 2023 Jan 6;2023(1):CD013778. doi: 10.1002/14651858.CD013778.pub2

Bavarsad 2015.

Study characteristics
Methods Study design: RCT
Study grouping: parallel‐group
Participants Baseline characteristics
IMT
  • N (randomized/analyzed): 20/15

  • Loss to follow‐up or excluded: 5

  • Age mean (SD) in years: 58.8 (6.82)

  • Gender (M/F): 13/2

  • BMI mean (SD), kg/m²: 24.88 (5.02)


Control/Sham
  • N (randomized/analyzed): 20/15

  • Loss to follow‐up or excluded: 5

  • Age mean (SD) in years: 54.2 (8.09)

  • Gender (M/F): 14/1

  • BMI mean (SD), kg/m²: 24.97 (4.72)


Overall
  • N (randomized/analyzed): 40/30

  • Loss to follow‐up or excluded: 10

  • Age range (min, max): 45, 65

  • Gender (M/F): 27/3

  • COPD stage (GOLD): mild to severe


Included criteria
  • Patients with spirometric evidence of significant chronic airflow limitation(FEV1/FVC < 70%pred) with mild to very severe COPD diagnosis according to the GOLD criteria;

  • Age range 45‑65 years;

  • No history of PR;

  • Established treatment plan 1 month prior to the study.


Excluded criteria
  • BMI > 35;

  • Comorbid conditions such as diabetes, musculoskeletal disorders, cardiovascular diseases; and neurological diseases that can affect the results of 6MWD;

  • Having exacerbation for 1 month prior to the study;

  • A history of long‑term oxygen therapy;

  • A history of spontaneous pneumothorax and rib fracture.

Interventions Intervention characteristics
IMT
The training consisted of unsupervised sessions, 15 min/d, 6 d/week for 8 weeks. The device used was an incentive spirometer (Respivol), at a load equal to or more than the initial inspiratory volume. The researchers were informed of the training sessions through phone calls during the 8 weeks. A checklist, which was designed to be completed on weekdays, was prepared for the participants so that they could mark the relevant day after a training session
Control
No intervention was received by this group.
Outcomes Dyspnea: Borg
  • Notes: dyspnea was assessed at the beginning and the end of the 6MWD


Functional exercise capacity: 6MWD
Respiratory function: FEV1 (%pred)
Respiratory function: FEV1 (L)
Identification Sponsorship source: The Deputy of Research Affairs at the Ahvaz Jundishapur University of Medical Sciences
Country: Iran
Setting: Specialized Pulmonary Clinic of Ahvaz
Author's name: Esmaeil Eidani
Institution: Pulmonary Unit, Department of Medicine, Ahvaz Jundishapur University of Medical Sciences
Email: esmaileidani@gmail.com
Address: Ahzav, Iran
Notes