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. 2023 Jan 6;2023(1):CD013778. doi: 10.1002/14651858.CD013778.pub2

Harver 1989.

Study characteristics
Methods Study design: RCT
Study grouping: parallel‐group
Participants Baseline characteristics
IMT
  • N (randomized/analyzed): not reported/10

  • Loss to follow‐up or excluded: not reported

  • Age, mean (SD) in years: 61.1 (9.5)

  • Gender (M/F): 8/2


Control/sham
  • N (randomized/analyzed): not reported/9

  • Loss to follow‐up or excluded: not reported

  • Age, mean (SD) in years: 64.8 (8.4)

  • Gender (M/F): 8/1


Overall
  • N (randomized/analyzed): 23/19

  • Loss to follow‐up or excluded: 4

  • Gender (M/F): 16/3

  • COPD stage (GOLD): moderate to severe


Included criteria
  • Participants for the study were recruited from the clinical practice of pulmonary physicians at the institution

  • Participants were stable both clinically and functionally, and medications were not changed during the study.


Excluded criteria: not reported
Interventions Intervention characteristics
IMT: participants trained twice a day, 15 min each session, 7 d/week, for 8 weeks. The training device was Pflex (with a controlled breathing pattern), and the training load ranged from 5 cmH2O to 35 cmH2O (≈30% PImax FRC)
Control/sham: this group received a similar IMT protocol with a training load set at 5cmH2O
Outcomes Dyspnea: BDI‐TDI: 
  • Functional impairment 

  • Magnitude of task 

  • Magnitude of effort

  • Focal score


Respiratory muscle strength: PImax 
  • RV

  • FRC


Respiratory function: FEV1
  • L


Respiratory muscle endurance: MVV
Identification Sponsorship source: The American Lung Association of New Hampshire and by grants HL07449 and HL29068 from the National Heart, Lung, and Blood Institute
Country: USA
Setting: Outpatient pulmonary clinic and pulmonary function laboratory
Author's name: Andrew Harver
Institution: Department of Psychology, SUNY Stony Brook
Address: Stony Brook, NY 11794
Notes