Hill 2007.

Study characteristics
Methods	Study design: RCT Study grouping: parallel‐group
Participants	Baseline characteristics IMT N (randomized/analyzed): 18/16 Loss to follow‐up or excluded: 2 Age, mean (SD) in years: 69.4 (7.2) Gender (M/F): 11/5 BMI, mean (SD), kg/m²: 24.9 (4.3) Control/sham N (randomized/analyzed): 17/17 Loss to follow‐up or excluded: 0 Age, mean (SD) in years: 66.6 (9.8) Gender (M/F): 11/6 BMI, mean (SD), kg/m²: 24.1 (3.7) Overall N (randomized/analyzed): 35/33 Loss to follow‐up or excluded: 2 Gender (M/F): 22/11 COPD stage (GOLD): severe to very severe Included criteria Participants who had a diagnosis of COPD Smoking history of 10 pack‐years  FEV1 ranging 15%–70% of predicted normal Excluded criteria Comorbid conditions likely to reduce exercise capacity (e.g. symptomatic ischemic heart disease, BMI > 35 kg.m²) Previous lung surgery The use of long‐term oxygen therapy Weaning doses of oral corticosteroids
Interventions	Intervention characteristics IMT: participants attended supervised training sessions 3 times/week for 8 weeks. Each session lasted 21 min and comprised 7 cycles of 2 min of breathing on an inspiratory threshold loading device (Threshold IMT; Respironics, Cedar Grove, NJ, USA) followed by 1 minute of rest. The training load was set at a range of around 45%‐101% of PImax Control/sham: this group received a similar IMT protocol with a training load set at 10% of PImax
Outcomes	Respiratory muscle endurance time: Tlim Respiratory muscle endurance pressure (Pthmax) Note: the same as Hill 2006
Identification	Sponsorship source: The National Health and Medica Research Council (Canberra, Australia) grant number 212016 Country: Australia Author's name: P.R. Eastwood Institution: Dept of Pulmonary Physiology, Sir Charles Gairdner Hospital Email: peter.eastwood@health.wa.gov.au Address: Hospital Avenue Nedlands Western Australia, Australia 6009
Notes