Tctr 2022.
| Study name | Effect of inspiratory muscle training on cardiovascular autonomic functions in chronic obstructive pulmonary disease patients |
| Methods |
Study design: RCT Study grouping: parallel‐group |
| Participants | Patients with COPD |
| Interventions |
IMT Home‐based IMT will be performed daily using PowerBreathe device. Total eight week of IMT will be provided. The IMT group will start training at 40% of their initial PImax. The new PImax value will be measured every week by the researcher. The training load in each week will be increased continuously over time by adjusting to at least 50% of PImax or gradually increase to the highest tolerable intensity during each of the supervised sessions. The highest tolerable intensity means that the rates of perceived inspiratory effort using a modified Borg dyspnea scale will be the range 4 to 6 of 10 (moderate to very severe). Daily training will consist of 2 sessions of 30 breaths.,The participants will receive only the standard care treatment from the physicians such as pharmacological treatment. They will meet the physician at week 1 and week 8. Control This group will not receive any intervention |
| Outcomes | Dyspnea:
Functional exercise capacity: 6MWD Respiratory muscle strength: PImax Spirometry measurements |
| Starting date | 2022 |
| Contact information | |
| Notes |
6MWD: six‐minute walk distance; ADL: activities of daily living; BMI: body mass index; CAT: Chronic Obstructive Pulmonary Disease Assessment Test; COPD: chronic obstructive pulmonary disease; CRQ: Chronic respiratory disease questionnaire; DBP: diastolic blood pressure; FEV1: forced expiratory volume at 1 second; FVC: forced vital capacity; GOLD: Global Initiative of Chronic Obstructive Lung Disease; HRQoL: health‐related quality of life; IMT: inspiratory muscle training; MIP: maximal inspiratory pressure; mMRC: Modified Medical Research Council; PImax: maximal inspiratory pressure; PR: pulmonary rehabilitation; RCT: randomized controlled trial; SBP: systolic blood pressure; SGRQ: St George's Respiratory Questionnaire; SMIP: sustained maximal inspiratory pressure; TIRE: test of incremental respiratory endurance