Table 8.
Distribution of the NF1 pathogenic variant types (truncating/nontruncating) between the SNF and classical groups.
| Mutation Type | SNF n (%) n = 67 | Classical NF n (%) n = 100 | p-Value | OR (95% CI) | Total Number |
|---|---|---|---|---|---|
| Truncating | 46 (68.7) | 83 (83) | 0.03 * | 0.44 (0.21–0.93) | 129 |
| Nontruncating | 19 (28.4) | 15 (15) | 0.036 | 2.24 (1.04–4.81) | 34 |
| Nd | 2 (3) | 2 (2) | 1 | 1.5 (0.2–10.97) | 4 |
In bold statistically significant p-values. * Statistically significant p-values with a false discovery rate of 0.05 after correction for multiple testing using the Benjamini–Hochberg procedure.