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. 2022 Dec 23;15(1):79. doi: 10.3390/cancers15010079

Table 4.

Excess relative rates * (ERR) of death from non-cancer diseases per unit (in Gray or Sievert) of 10-year lagged cumulative dose absorbed to target tissues (in Gy or Sv) in males only, SELTINE cohort, period 1968–2014.

Cause of Death Target
Tissue
Observed
Deaths
ERR/Gy
or ERR/Sv
95% CI p-Value
Non-cancer diseases (all) Hp(10) 8577 0.02 −0.49; 0.57 0.95
Diabetes mellitus Hp(10) 169 −0.91 ne; 2.62 0.54
Mental and behavioural disorders Brain 235 2.74 −1.95; 10.33 0.32
Diseases of the nervous system Brain 531 3.47 −0.48; 8.56 0.09
Dementia, Alzheimer’s disease, Parkinson’s disease, motoneuron disease Brain 469 4.99 0.74; 10.52 0.02
Dementia, Alzheimer’s disease Brain 269 9.62 3.05; 18.68 <0.01
Parkinson’s disease Brain 124 −1.30 ne; 7.44 0.71
Circulatory diseases Hp(10) 3261 0.09 −0.72; 1.03 0.83
Ischemic diseases Hp(10) 1258 −0.23 ne; 1.38 0.76
Cerebrovascular diseases Hp(10) 684 1.41 ne; 4.05 0.19
Hypertensive diseases Hp(10) 120 2.31 ne; 9.98 0.37
Respiratory diseases Lung 558 0.22 ne; 3.71 0.88
Chronic obstructive pulmonary diseases Lung 164 0.15 ne; 7.52 0.96
Digestive diseases Colon 583 0.96 −1.72; 4.58 0.53
Cirrhosis Liver 166 3.72 ne; 13.64 0.29

* estimated from a linear model of cumulative penetrating photon dose lagged by 10 years, adjusted on calendar year, age, sex, company, duration of employment, and socioeconomic status; CI: likelihood-based confidence interval; ne: not estimated.