Table 1.
PTMs | TAA | Type of Tumor in Which TAA Has Been Identified or to Which the Antigen Is Associated | Immune Recognition (If Any) | References |
---|---|---|---|---|
Acetylation | ENO1 | Pancreas | NA | [16] |
p53 | Colon, Prostrate, Pharynx | CD4+ T Cell | [19] | |
Phosphorylation | MART-1 | Melanoma, Leukemia | CD4+ T Cell | [29] |
IRS2 | Melanoma, Breast, Ovary, Colon | CD8+ T Cell | [18,30,31] | |
β-Catenin | Ovary, Melanoma | CD8+ T Cell | [30,31] | |
Breast cancer antiestrogen resistance 3 | Melanoma | CD8+ T Cell | [30] | |
p53 | Head and Neck | CD4+ T Cell | [21] | |
ENO1 | Pancreas | Ab, CD4+ T Cell | [14,15] | |
CDC25b | Melanoma, Breast, Ovary, Colon, Leukemia | CD8+ T Cell | [18,31] | |
TNF receptor associated protein (TRAP-1) | Lung | CD8+ T Cell | [32] | |
Vim | Colon | CD4+ T cells | [33] | |
Citrullination | Vim | Melanoma, Lung | CD4+ T Cell | [17,34,35,36] |
Enolase | Melanoma, Lung | CD4+ T Cell | [17,35,36,37] | |
Glycosylation | MUC1 | Breast, Ovary | CD8+ T Cell, Ab |
[38,39] |
Sialylation | Silayl-Tn-Antigen | Breast, Ovary | Ab (IgM) | [40,41,42,43] |
SUMOylation | p53 | Sarcoma | NA | [44] |
Methylation | Enolase | Pancreas | NA | [16] |