FIG. 1.
Kinetics of anti-LPS and antiglycolipid reactivity in rabbits immunized with C. jejuni LPS. Sequential serum samples were tested for IgM and IgG reactivity against C. jejuni LPS and glycolipids. (A and B) For rabbits 1 and 2, anti-GM1, anti-GA1, and anti-GB17 LPS reactivity and IgM and IgG reactivity rose in parallel and were at high levels after 14 days. (C and D) For rabbits 3 and 4, anti-GM1 and anti-GB18 LPS IgM antibody reactivity decreased after an initial rise, while IgG reactivity continued to rise. The kinetics of anti-GA1 reactivity differed from that of anti-GM1 reactivity in rabbit 4. (E and F) For rabbits 5 and 6, the kinetics of anti-GA1 reactivity differed from that of anti-GM1 reactivity in rabbit 4. The kinetics of anti-GQ1b and anti-MF6 LPS IgM reactivity were similar. The kinetics of anti-GQ1b IgG and anti-GA1 IgG reactivity were different compared to anti-MF6 LPS IgG reactivity. OD, optical density.