FIG. 3.

Identical pattern of cross-reactivity of antiganglioside and anti-LPS antibodies in patients and immunized rabbits. Sera from patient MF6 and from rabbit 5, immunized with MF6 LPS, were incubated with Sepharose CL4B beads that were coated with C. jejuni LPS, and diluted serum samples were tested for residual reactivity against GQ_1b and MF6 LPS. The specificities of both human and rabbit sera are identical. Anti-GQ_1b reactivity in the rabbit and the patient was reduced only by incubation with MF6 LPS-coated beads (solid circles in panels A and B). The same pattern could be observed when sera were tested for anti-MF6 LPS reactivity (C and D). OD, optical density.