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. 2022 Dec 28;12(1):119. doi: 10.3390/cells12010119

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Spatial memory levels improved in Old treated mice in Forced Alternation Y-maze. Data is presented as mean ± SEM. Old Tg-FO (n = 8) and Old Tg-FY (n = 8) demonstrated increased (a) exploration time in Novel arm and (b) Ratio of Novel to Open arm entries (p < 0.05 compared to Old Tg-Control (n = 7)). (c,d) Young Tg-FY (n = 8) did not show improvement in FAY compared to Young Tg-Control (n = 7). WT values are presented for comparison only. Young Tg-FY: Young Transgenic-Fed Young, Young Tg-Control: Young Transgenic Control, Old Tg-FY: Old Transgenic-Fed Young, Old Tg-FO: Old Transgenic-Fed Old, Old Tg-Control: Old Transgenic Control, Young WT: Young Wildtype, Old WT: Old Wildtype.

Spatial memory levels improved in Old treated mice in Forced Alternation Y-maze. Data is presented as mean ± SEM. Old Tg-FO (n = 8) and Old Tg-FY (n = 8) demonstrated increased (a) exploration time in Novel arm and (b) Ratio of Novel to Open arm entries (p < 0.05 compared to Old Tg-Control (n = 7)). (c,d) Young Tg-FY (n = 8) did not show improvement in FAY compared to Young Tg-Control (n = 7). WT values are presented for comparison only. Young Tg-FY: Young Transgenic-Fed Young, Young Tg-Control: Young Transgenic Control, Old Tg-FY: Old Transgenic-Fed Young, Old Tg-FO: Old Transgenic-Fed Old, Old Tg-Control: Old Transgenic Control, Young WT: Young Wildtype, Old WT: Old Wildtype.