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. 2022 Dec 30;12(1):160. doi: 10.3390/cells12010160

Figure 1.

Figure 1

Three-weeks of SF activates microglia in the HP. (A): Schematic for the experimental design. (B): Iba1 immunostaining for purified adult Mg. (C,D): Significant enrichment of pro-inflammatory mediators in purified Mg compared to homogenates from the HP and PFc (n = 6, * p < 0.05). (E–G): levels of four pro-inflammatory mediators in purified Mg isolated from the striatum, HP, and PFc of SF and sham mice. (n = 6, * p < 0.05, sham vs. SF). (H–J): levels of four pro-inflammatory mediators in the homogenates prepared from the striatum, HP, and PFc of SF and sham mice (n = 6, * p < 0.05, sham vs. SF).