Table 2.
PUFA | Abbreviation | PUFA Type | Oxylipins Produced by CYPs |
---|---|---|---|
Linoleic acid | LA | n-6 | EpOME, DiHOME, HpODE, HODE, oxoODE |
Arachidonic acid | AA | n-6 | HETE, oxoETE, EET, DiHET |
alpha-linolenic acid | ALA | n-3 | EpODE, DiHODE, HpOTrE, HOTrE, oxoOTrE |
Eicosapentaenoic acid | EPA | n-3 | EpETE, DiHETE, HEPE |
Docosahexaenoic acid | DHA | n-3 | EpDPA, DiHDPA |
Epoxyoctadecamonoenoic acid (EpOME), dihydroxyoctadecenoic acid (DiHOME), hydroperoxy-octadecadienoic acid (HpODE), hydroxy-octadecadienoic acid (HODEs), oxo-octadecadienoic acid (oxoODE), hydroxyeicosatetraenoic acid (HETE), oxoicosatetraenoic acid (oxoETE), epoxyeicosatrienoic acid (EET), dihydroxyeicosatrienoic acids (DiHETs), epoxy-octadecadienoic acid (EpODE), dihydroxy-octadecadienoic acid (DiHODE), hydroperoxy-octadecatrienoic acid (HpOTrE), hydroxy-octadecatrienoic acid (HOTrE), oxo-octadecatrienoic acid (oxoOTrE), epoxy-eicosatetraenoic acid (EpETE), dihydroxy-eicosatetraenoic acid (DiHETE), hydroxyicosapentaenoic acid (HEPE), epoxy-docosapentaenoic acid (EpDPA), dihydroxy-docosapentaenoic acid (DiHDPA).