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. 2022 Dec 24;12(1):82. doi: 10.3390/cells12010082

Table 2.

Primary CYP-mediated oxylipins produced from different PUFAs.

PUFA Abbreviation PUFA Type Oxylipins Produced by CYPs
Linoleic acid LA n-6 EpOME, DiHOME, HpODE, HODE, oxoODE
Arachidonic acid AA n-6 HETE, oxoETE, EET, DiHET
alpha-linolenic acid ALA n-3 EpODE, DiHODE, HpOTrE, HOTrE, oxoOTrE
Eicosapentaenoic acid EPA n-3 EpETE, DiHETE, HEPE
Docosahexaenoic acid DHA n-3 EpDPA, DiHDPA

Epoxyoctadecamonoenoic acid (EpOME), dihydroxyoctadecenoic acid (DiHOME), hydroperoxy-octadecadienoic acid (HpODE), hydroxy-octadecadienoic acid (HODEs), oxo-octadecadienoic acid (oxoODE), hydroxyeicosatetraenoic acid (HETE), oxoicosatetraenoic acid (oxoETE), epoxyeicosatrienoic acid (EET), dihydroxyeicosatrienoic acids (DiHETs), epoxy-octadecadienoic acid (EpODE), dihydroxy-octadecadienoic acid (DiHODE), hydroperoxy-octadecatrienoic acid (HpOTrE), hydroxy-octadecatrienoic acid (HOTrE), oxo-octadecatrienoic acid (oxoOTrE), epoxy-eicosatetraenoic acid (EpETE), dihydroxy-eicosatetraenoic acid (DiHETE), hydroxyicosapentaenoic acid (HEPE), epoxy-docosapentaenoic acid (EpDPA), dihydroxy-docosapentaenoic acid (DiHDPA).