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Depleting PCSK9 impairs liver tumor development in vivo. In zebrafish experiments: tomato red fluorescent labeled HepG2 with shPCSK9 or the control were xenografted in zebrafish embryos. Tumoral cell growth was evaluated by the quantification of the fluorescence 24 and 48 h post-injection (hpi). Unpaired t-test, *: p < 0.05, ****: p < 0.0001.
