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. 2022 Dec 22;12(1):48. doi: 10.3390/cells12010048

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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STRING Interactome of the up-regulated proteins in the contrast RC vs. SC. Each node in the graph represents a protein. Edges represent experimentally proven physical interactions with high confidence. Singletons, i.e., up-regulated proteins whose interactors are not up-regulated, are not displayed. Colors identify different clusters generated by Markov Cluster Algorithm (MCL) with parameter 1.3. Clusters particularly relevant for plasticity are highlighted as convex hulls of a different color and the names of particularly relevant genes/hubs are also displayed.