Table 3.
Hazard ratios (HR) for 5-year all-cause mortality with 95% confidence intervals in pulmonary metastases and primary colorectal tumours stratified by ICS (0/1/2).
| n | ICS 0, HR (95%CI) | ICS 1, HR (95%CI) | ICS 2, HR (95%CI) | |
|---|---|---|---|---|
| Metastases | ||||
| Crude | 67 | 1.00 (reference) | 0.48 (0.22–1.03, p = 0.058) | 0.31 (0.12–0.84, p = 0.022) |
| Adjusted * | 67 | 1.00 (reference) | 0.31 (0.13–0.74, p = 0.008) | 0.25 (0.09–0.75, p = 0.013) |
| Primary Tumours | ||||
| Crude | 62 | 1.00 (reference) | 0.63 (0.29–1.35, p = 0.233) | 1.31 (0.53–3.24, p = 0.558) |
| Adjusted ** | 62 | 1.00 (reference) | 0.69 (0.28–1.67, p = 0.406) | 1.35 (0.41–4.42, p = 0.625) |
* Adjusted for sex (male/female), age (continuous), CCI (1/≥2), Neoadjuvant chemotherapy (no/yes), number of pulmonary metastases at diagnosis (1/2/≥3) and synchronicity of first resected pulmonary metastases (synchronous/metachronous), former liver metastasectomy (yes/no). ** Adjusted for sex(male/female), age (continuous), CCI (1/2/≥3), Neoadjuvant therapy (no/yes), CRC stage (I-II/III/IV), CRC location (colon/rectum) and CRC grade (1/2/3).