Figure 1.

Successful establishment of a model of AP in Rat and cell lines. (A,B) The establishment of the rat model of acute pancreatitis was confirmed by HE staining, the pathological scoring was performed in two groups, n = 5 in each group, and representative images have been shown. (C,D) Apoptosis of pancreatic tissues in rats evaluated by TUNEL staining (n = 5). (E,F) Serum levels of AMY and LIPA of rats examined by ELISA (n = 5). (G–I) Expression of IL-6, TNF-α, and IL-1β in the rats, AR42J, and HPDE6-C7 assessed by ELISA (n = 3). The data are presented as means ± SDs, * p < 0.05; ** p < 0.01; *** p < 0.001, between the indicated groups.