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. 2022 Dec 24;12(1):65. doi: 10.3390/cells12010065

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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MiR-7-5p binds to lncRNA-SNHG11 in pancreatic cells. (A) Prediction of potentially downstream miRNAs bound to SNHG11 by Annolnc, Encori, and Diana databases. (B) Prediction of the binding position of SNHG11 and miR-7-5p through the secondary structure of SNHG11. (C) Schematic diagram of the MUT-SNHG11 plasmid. (D–G) The relationship between SNHG11 and miR-7-5p was verified by dual-luciferase reporter assay and RIP assay in AR42J and HPDE6-c7 cells. (H–J) The expression of miR-7-5p was assessed in rat tissues, AR42J, and HPDE6-C7 cells. The data are presented as means ± SDs, n = 3 for each group, * p < 0.05; ** p < 0.01; *** p < 0.001, ns = no significance between the indicated groups.