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. 2022 Dec 24;12(1):65. doi: 10.3390/cells12010065

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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LncRNA-SNHG11 plays a role in pancreatitis through MiR-7-5p. (A,B) The regulation effect of SNHG11 expression on MiR-7-5p was observed in AR42J and HPDE6-C7 cells. (C,D) The expression of miR-7-5p in different pancreatitis cell models was verified. (E,F) Cell proliferation was assessed by CCK8 assay in AR42J and Hpde6-C7 Cell models. (G–J) The effects of SNHG11 on cell death and apoptosis in AR42J and HPDE6-C7 cell models were observed by Trypan blue assay and Flow cytometry assay. (K,L) Expression of IL-6, TNF-α, and IL-1β in the AR42J and HPDE6-C7 cell lines assessed by ELISA. The data are presented as means ± SDs, n = 3 for each group, * p < 0.05; ** p < 0.01; *** p < 0.001, NS = no significance, between the indicated groups.