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. 2022 Dec 20;20(1):26. doi: 10.3390/ijerph20010026

Table 4.

Total, direct, and indirect effects (unstandardized estimates) of the mediation models examining the association between negative affect (anxiety, depression, and stress) and physical and mental health-related quality of life with sleep quality as mediator.

Estimate (SE) t a 95% CI b
Total effect
DASS-21 anxiety → PCS −0.57 (0.09) −6.17 *** [−0.75, −0.39]
DASS-21 depression → PCS −0.13 (0.08) −1.52 [−0.30, 0.04]
DASS-21 stress → PCS 0.13 (0.10) 1.27 [−0.07, 0.33]
DASS-21 anxiety → MCS 0.13 (0.11) 1.12 [−0.09, 0.35]
DASS-21 depression → MCS −0.70 (0.10) −7.34 *** [−0.96, −0.55]
DASS-21 stress → MCS −0.64 (0.12) −5.18 *** [−0.88, −0.40]
Direct effect
DASS-21 anxiety → PCS −0.52 (0.09) −5.63 *** [−0.70, −0.34]
DASS-21 depression → PCS −0.09 (0.08) −1.10 [−0.26, 0.07]
DASS-21 stress → PCS 0.18 (0.10) 1.75 [−0.02, 0.38]
DASS-21 anxiety → MCS 0.17 (0.11) 1.50 [−0.05, 0.39]
DASS-21 depression → MCS −0.72 (0.10) −7.01 *** [−0.93, −0.52]
DASS-21 stress → MCS −0.60 (0.12) −4.80 *** [−0.84, −0.35]
Indirect effect
DASS-21 anxiety → PSQI → PCS −0.05 (0.02) [−0.10, −0.01]
DASS-21 depression → PSQI → PCS −0.04 (0.02) [−0.08, −0.003]
DASS-21 stress → PSQI → PCS −0.05 (0.02) [−0.10, −0.01]
DASS-21 anxiety → PSQI → MCS −0.04 (0.02) [−0.10, −0.01]
DASS-21 depression → PSQI → MCS −0.03 (0.02) [−0.07, −0.001]
DASS-21 stress → PSQI → MCS −0.04 (0.02) [−0.10, −0.004]

Note. PSQI: Pittsburgh Sleep Quality Index; DASS-21: 21-item Depression Anxiety Stress Scale; PCS: Short Form-12 Physical Component Summary; MCS: Short Form-12 Mental Component Summary. *** p < 0.001. a: t statistics and relative p-values were computed only for total effects and direct effects. b: 95% percentile bootstrap confidence intervals are reported for indirect effects.