TABLE 4.

Enhancement of in vitro growth-inhibitory activity of MAb SP8.18 by noninhibitory MAbs SP5.2, RAP1-7, and RAP1-14^a

MAb or MAb combination	Concn (μg/ml)	% Inhibition	95% CI
SP8.18	500	39.3	34–44.2
SP8.18 + SP5.2	500	56.7	47.7–64.1
SP8.18 + RAP1-14	500	56.3	49.5–62.1
SP8.18	350	23.7	−2.9–43.4
SP8.18 + RAP1-7	350	50.9	34–63.5
SP8.18 + RAP1-14	350	49.2	31.2–62.5

^aMAb SP8.18 was mixed with a second MAb and added to the parasite culture. Experiments were performed in sextuplicate, and inhibition was calculated as explained in the footnotes of Table 3. CI, confidence interval.